Network degeneration of FTLD Lead Investigator: David Irwin Institution : University of Pennsylvania E-Mail : dirwin@mail.med.upenn.edu Proposal ID : 1103 Proposal Description: The goal of this project is to compare the regional patterns of disease in patients with FTLD-Tau and FTLD-TDP pathology. We will compare regional patterns of GM atrophy and WM loss on DTI in patients with autopsy/genetic confirmed FTLD-Tau and FTLD-TDP. We request MRI imaging data.